FIGURE 1. Pharmacokinetically Guided Leucovorin Rescue After HDMTX Administration

HDMTX = high-dose methotrexate; hr = hour; MTX = methotrexate.
Adapted from Baer DM, Dita WR, eds. Interpretations in Therapeutic Drug Monitoring. Chicago, IL: American Society of Clinical Pathology; 1981:169-181.