Diagnostic errors remain a significant challenge in healthcare, impacting patient outcomes and eroding trust. Risk and Safety Issues in Inpatient Pediatrics XVII offers pediatric healthcare professionals a variety of strategies they can use to offset these risks, including: (1) diagnostic time-outs to reduce cognitive bias and improve accuracy; (2) metacognition techniques to critically evaluate their diagnostic thought processes; (3) collaboration to improve diagnostic precision, and (4) patient/family engagement to increase accuracy and stakeholder satisfaction.